Endometriosis is a chronic inflammatory disease. Although the exact pathophysiology of the disease is unknown, one of the possible causes is believed to be a blockage in the sympathetic nervous system. Cytokines and inflammatory markers, which are secreted upon inflammatory process triggered by a blockage in the sympathetic nervous system, as well as tissue deformation and organ perfusion, contribute to formation of both disease and pain. Moreover, a blockage in sympathetic nervous system affects the hypothalamic pituitary adrenal axis and leads to its deregulation. Consequent secretion of stress factors increase levels of cortisol, which possess an analgesic effect. While the therapy we apply for treatment of endometriosis includes regulation of sympathetic nervous system affecting the hormonal axis, neural therapy is a regulation treatment by local anesthetics (procaine-lidocaine). Purpose Induced endometriosis, chronic pelvic pain and the relief of pain associated with other symptoms indicate the effectiveness of neuraltherapy Method Neuraltherapy to patients who were diagnosed endometriosis and pain associated symptoms was applied. Clinical findings In our study, we included 50 volunteer endometriosis patients. If the cause of endometriosis is a hormonal dysfunction Hormonal therapy, which will be held axle (pituitary, celiac ganglion, thyroid, uterovaginalis plexus) is the first step of treatment. In order to increase tissue perfusion and innervation of the pelvic region of all to regulate with local and segmental treatment scarring in the pelvis in all possible inclusion in the treatment of tissues in the same area again Results Stimulation of sympathetic nervous system has an anti-inflammatory effect in the body. Thus, pathophysiological mechanisms leading to endometriosis are removed.